Phosphorescence-based O2 sensing reveals size-dependent survival and motility of metastatic prostate cancer cells in self-generated hypoxia
Summary: Cancer cells in solid tumors experience hypoxia, a condition of low O2 concentration, since Celiac their O2 demand exceeds the supply from the surrounding vasculature.However, how these cells adapt to hypoxia requires further elucidation.Here, we use a transparent phosphorescent thin film to visualize the self-generated hypoxia field of pr